Original Articles: 2017-now
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Biophysical Mechanism of Allosteric Regulation of Actin Capping Protein.Mooren, O. L., Stuchell-Brereton, M. D., McConnell, P., Yan, C., Wilkerson, E. M., Goldfarb, D., Cooper, J. A., Sept, D. & Soranno, A. 2023. J Mol Biol 435: 168342. Online Link.
Actin capping protein regulates postsynaptic spine development through CPI-motif interactions. Myers, K. R., Fan, Y., McConnell, P., Cooper, J. A. & Zheng, J. Q. 2022. Front Mol Neurosci 15: 1020949. Online Link.
CARMIL3 is important for cell migration and morphogenesis during early development in zebrafish. Stark, B. C., Gao, Y., Sepich, D. S., Belk, L., Culver, M. A., Hu, B., Mekel, M., Ferris, W., Shin, J., Solnica-Krezel, L., Lin, F. & Cooper, J. A. 2021. Dev Biol. S0012-1606(21)00215. Online Link.
Targeting primary and metastatic uveal melanoma with a G protein inhibitor. Onken, M. D., Makepeace, C. M., Kaltenbronn, K. M., Choi, J., Hernandez-Aya, L., Weilbaecher, K. N., Piggott, K. D., Rao, P. K., Yuede, C. M., Dixon, A. J., Osei-Owusu, P., Cooper, J. A. & Blumer, K. J. 2021. J Biol Chem 296: 100403.Online Link.
Uveal melanoma cells use ameboid and mesenchymal mechanisms of cell motility crossing the endothelium. Onken, M.D. et al. 2021.Mol. Biol. Cell 32:413-421. Online Link.
Junctional Localization of Septin 2 Is Required for Organization of Junctional Proteins in Static Endothelial Monolayers. Kim, J. & Cooper, J. A. 2021.Arterioscler Thromb Vasc Biol.41:346-359. Online Link.
Comparative analysis of CPI-motif regulation of biochemical functions of actin capping protein. McConnell, P., Kozlov, A., Mekel, M., Mooren, O. L., Lohman, T. M. & Cooper, J. A. 2020.Biochemistry 59:1202-15.
Transposase mapping identifies the genomic targets of BAP1 in uveal melanoma. Yen, M., Qi, Z., Chen, X., Cooper, J. A., Mitra, R. D. & Onken, M. D. 2018. BMC Med Genomics 11: 97.
A novel mode of Capping Protein-regulation by Twinfilin. Johnston, A. B., Hilton, D. M., McConnell, P., Johnson, B., Harris, M. T., Simone, A., Amarasinghe, G. K., Cooper, J. A. & Goode, B. L. 2018. Elife 7: e41313.
Targeting nucleotide exchange to inhibit constitutively active G protein α subunits in cancer cells. Onken, Makepeace, Kaltenbronn, Kanai, Todd, Wang, Broekelmann, Rao, Cooper & Blumer. 2018. Sci Signal 11: eaao6852.
Septins regulate junctional integrity of endothelial monolayers. Kim, J. & Cooper, J. A. 2018. Mol Biol Cell doi: 10.1091/mbc.E18-02-0136.
Allosteric Coupling of CARMIL and V-1 Binding to Capping Protein Revealed by Hydrogen/Deuterium Exchange. Johnson, B. et al. 2018. Cell Reports 23: 2795-804.
New in vitro method for assaying the migration of primary B cells using an endothelial monolayer as substrate. Stewart-Hutchinson, P. J. et al. 2017. J Leukoc Biol 102: 941-48.
Mst1 Kinase Regulates the Actin-Bundling Protein L-Plastin To Promote T Cell Migration. Xu, X. et al. 2016. J Immunol 197: 1683-91.
L-Plastin promotes podosome longevity and supports macrophage motility. Zhou, J. Y. et al. 2016. Mol Immunol 78: 79-88.
Trojan Horse Transit Contributes to Blood-Brain Barrier Crossing of a Eukaryotic Pathogen. Santiago-Tirado, F. H. et al. 2017. mBio 8: e02183-16.
      
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